How It Works | ESTRING® (estradiol vaginal ring) | Safety Info

How ESTRING Works

ESTRING® (estradiol vaginal ring) is a local therapy designed to relieve moderate-to-severe itching, burning, and dryness in and around the vagina due to atrophy after menopause. Once inserted (either by you or your doctor), the ring will begin to release the estrogen hormone estradiol. It will continue to release a low, continuous dose for the full 90 days that ESTRING remains in place.

How ESTRING Works

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*Do not use ESTRING® (estradiol vaginal ring) if you are allergic to
any of these ingredients: estradiol, silicone polymers, or barium sulfate.

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One Application—90 Days of Treatment

ESTRING is an off-white, soft, flexible ring with a core that contains 2 mg of estradiol (an estrogen hormone).

Each ESTRING ring lasts for 90 days. After that, there won’t be enough estradiol left to provide you with relief, so the ring should be taken out.

Keep in mind that estrogens such as ESTRING should be used only as long as needed. You and your healthcare professional should talk regularly (for example, every 3 to 6 months) about whether you still need treatment with ESTRING.

How Long ESTRING Takes to Work

After you start using ESTRING, be patient. It may take about 2 to 3 weeks to restore the tissue of the vagina and urinary tract to a healthier condition. It can also take that long to feel the full effect of ESTRING in relieving your symptoms. If your symptoms persist for more than a few weeks after beginning ESTRING therapy, contact your doctor or healthcare professional.