How does Estring work

ESTRING® (estradiol vaginal ring) is a local therapy designed to relieve itching, burning, and dryness in and around the vagina. Once inserted (either by you or your doctor), the ring will begin to release the estrogen hormone, estradiol. It will continue to release a low, continuous dose for the full 90 days that ESTRING remains in place.


When ESTRING is in place, you should not feel it. In a US study, 95% of women who used the product for 12 weeks rated the comfort of ESTRING as “excellent” or “very good.”


What’s it made of?

ESTRING contains estradiol, silicone polymers, and barium sulfate, which are combined to form the ring. Do not use ESTRING if you are allergic to any of these ingredients.


One application for 3 months of treatment

Each ESTRING ring lasts 90 days. After that, there won’t be enough estradiol left to provide you with relief, so the ring should be taken out.


NOTE: Carefully follow instructions for use. If you have difficulty removing ESTRING, contact your healthcare provider right away.


Keep in mind that estrogens such as ESTRING should be used only as long as needed. You and your healthcare provider should talk regularly (for example, every 3 to 6 months) about whether you still need treatment with ESTRING.

Next Section: How to Use ESTRING >

INDICATION

ESTRING® (estradiol vaginal ring) is used after menopause to treat moderate to severe vaginal itching, burning and dryness, painful intercourse, urinary urgency, and painful urination due to urogenital atrophy.

Important Safety Information

Estrogens increase the risk of cancer of the uterus. It is important that you report any unusual vaginal bleeding to your doctor right away. Do not use estrogens with or without progestins to prevent heart disease, heart attacks, strokes, or dementia. Using estrogens with or without progestins may increase your risk of heart attack, stroke, breast cancer, or blood clots. Using estrogens with or without progestins may increase your risk of dementia, based on a study of women aged 65 years or older. Estrogens should only be used for as long as needed. You and your healthcare provider should talk regularly about whether you still need treatment with ESTRING.


ESTRING should be removed after 90 days of continued use.

Do not use ESTRING if you have unusual vaginal bleeding, have or have had cancer of the breast or uterus, had a stroke or heart attack, have or have had blood clots or liver problems, are allergic to any of its ingredients, or think you may be pregnant.

The most frequently reported side effects are headaches, increased vaginal secretions, vaginal discomfort, abdominal pain, and genital itching.

Call your healthcare provider right away if you have any of the following warning signs: breast lumps, unusual vaginal bleeding, dizziness and faintness, changes in speech, severe headaches, chest pain, shortness of breath, pain in your legs, or changes in vision.

Carefully follow instructions for use. If you have difficulty removing ESTRING, contact your healthcare provider right away.

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